Growth curves of children with Down syndrome.

Annales de genetique Pub Date : 1999-01-01
C Toledo, Y Alembik, A Aguirre Jaime, C Stoll
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Abstract

Growth curves of 105 children with Down syndrome (50 boys and 55 girls) were established. At birth height, weight and head circumference of Down syndrome children were lower than these parameters in controls. This delay remained stable until puberty. For weight there was no clear-cut pubertal growth spurt. For stature, the prepubertal growth spurt occurred earlier (at the age of 11 years in boys and 9 1/2 years in girls) than in controls but was less marked. As a result, Down syndrome patients had a short stature with a quite normal weight. These reference curves, available since prenatal diagnosis of Down syndrome is performed routinely, are helpful for monitoring normal and abnormal development in Down syndrome patients.

唐氏综合症儿童的生长曲线。
建立105例唐氏综合征患儿(男50例,女55例)的生长曲线。唐氏综合征患儿出生时身高、体重和头围均低于对照组。这种延迟一直持续到青春期。体重方面没有明显的青春期生长突增。就身材而言,青春期前的生长突增比对照组发生得更早(男孩为11岁,女孩为9岁半),但不那么明显。因此,唐氏综合症患者身材矮小,体重正常。由于唐氏综合征的产前诊断是常规的,这些参考曲线有助于监测唐氏综合征患者的正常和异常发育。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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