Recurrent adrenocortical carcinoma in a child.

B Trsinar, C Oblak, V Smrkolj
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引用次数: 0

Abstract

An 8-month-old girl presented with clitoromegaly, cushingoid features and a large abdominal tumour. Ultrasonography (US) and computed tomography (CT) of the abdomen revealed a tumour of the left suprarenal gland, 12x11x7 cm in size. Serum levels of cortisol, testosterone and DHEA-S, and urinary extretion of 17-ketosteroids and 17-hydroxycorticoids were increased. Complete removal of the tumour was accomplished through a transabdominal approach. The diagnosis of adrenocortical carcinoma was confirmed histologically. Three months after the first operation, a recurrent tumour of the left renal hilus, 23x15 mm in size, was identified by US and verified by aspiration biopsy. The tumour was removed by the transabdominal route. In this report, we discuss the diagnosis and the treatment of this rare disease.

儿童复发性肾上腺皮质癌一例。
一个8个月大的女孩表现为阴蒂肿大,库欣样特征和一个大的腹部肿瘤。腹部超声及CT示左侧肾上腺肿瘤,大小12x11x7cm。血清皮质醇、睾酮、DHEA-S水平升高,尿中17-酮类固醇和17-羟基皮质激素含量升高。通过经腹入路完成肿瘤的完全切除。经组织学检查证实为肾上腺皮质癌。第一次手术后3个月,左肾门复发肿瘤,23x15mm大小,经超声确认,并经穿刺活检证实。经腹部切除肿瘤。在这篇报道中,我们讨论了这种罕见疾病的诊断和治疗。
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