Anorectal manometry during the neonatal period: its specificity in the diagnosis of Hirschsprung's disease.

IF 1.5 3区 医学 Q2 PEDIATRICS
H Emir, M Akman, N Sarimurat, N Kiliç, E Erdoğan, Y Söylet
{"title":"Anorectal manometry during the neonatal period: its specificity in the diagnosis of Hirschsprung's disease.","authors":"H Emir,&nbsp;M Akman,&nbsp;N Sarimurat,&nbsp;N Kiliç,&nbsp;E Erdoğan,&nbsp;Y Söylet","doi":"10.1055/s-2008-1072221","DOIUrl":null,"url":null,"abstract":"<p><p>In this study the reliability of anorectal manometry (ARMM) in Hirschsprung's disease (HD) in the neonatal period is evaluated. ARMM was performed in 59 patients (age ranging between 2 to 90 days) in whom HD was suspected. Rectal biopsy was performed in 23 newborn whose rectoanal inhibitory reflex (RAIR) was not identified in the ARMM study and in 13 RAIR-positive newborn due to strong clinical signs supporting HD or persistence of symptoms during their follow-up. Other RAIR-positive patients were followed up to 4 months to 3.5 years and no problems were encountered. Among the 36 newborn with rectal biopsies, if the results were compared to ARMM studies, there were one false-positive and two false-negative results. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of ARMM in the diagnosis of HD are 91.6%, 95.6%, 84.6% and 91.6% respectively. We conclude that ARMM can be used as a screening test in patients in whom HD is suspected during the neonatal period, but for definitive diagnosis it must be combined with other diagnostic tests.</p>","PeriodicalId":56316,"journal":{"name":"European Journal of Pediatric Surgery","volume":"9 2","pages":"101-3"},"PeriodicalIF":1.5000,"publicationDate":"1999-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2008-1072221","citationCount":"57","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Pediatric Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/s-2008-1072221","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 57

Abstract

In this study the reliability of anorectal manometry (ARMM) in Hirschsprung's disease (HD) in the neonatal period is evaluated. ARMM was performed in 59 patients (age ranging between 2 to 90 days) in whom HD was suspected. Rectal biopsy was performed in 23 newborn whose rectoanal inhibitory reflex (RAIR) was not identified in the ARMM study and in 13 RAIR-positive newborn due to strong clinical signs supporting HD or persistence of symptoms during their follow-up. Other RAIR-positive patients were followed up to 4 months to 3.5 years and no problems were encountered. Among the 36 newborn with rectal biopsies, if the results were compared to ARMM studies, there were one false-positive and two false-negative results. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of ARMM in the diagnosis of HD are 91.6%, 95.6%, 84.6% and 91.6% respectively. We conclude that ARMM can be used as a screening test in patients in whom HD is suspected during the neonatal period, but for definitive diagnosis it must be combined with other diagnostic tests.

新生儿期肛门直肠测压:其诊断先天性巨结肠病的特异性。
本研究评估了新生儿期肛管直肠测压法(ARMM)在先天性巨结肠病(HD)诊断中的可靠性。对59例怀疑患有HD的患者(年龄在2至90天之间)进行了ARMM检查。对23名在ARMM研究中未发现直肠抑制反射(RAIR)的新生儿和13名RAIR阳性的新生儿进行了直肠活检,原因是有强烈的临床迹象支持HD或在随访期间症状持续存在。其他rair阳性患者随访4个月至3.5年,均未出现问题。在36例新生儿直肠活检中,如果将结果与ARMM研究进行比较,则有1例假阳性和2例假阴性结果。ARMM诊断HD的敏感性为91.6%,特异性为95.6%,阳性预测值为84.6%,阴性预测值为91.6%,准确率为91.6%。我们的结论是,ARMM可用于新生儿期怀疑患有HD的患者的筛查试验,但为了明确诊断,必须与其他诊断试验相结合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
3.90
自引率
5.60%
发文量
66
审稿时长
6-12 weeks
期刊介绍: This broad-based international journal updates you on vital developments in pediatric surgery through original articles, abstracts of the literature, and meeting announcements. You will find state-of-the-art information on: abdominal and thoracic surgery neurosurgery urology gynecology oncology orthopaedics traumatology anesthesiology child pathology embryology morphology Written by surgeons, physicians, anesthesiologists, radiologists, and others involved in the surgical care of neonates, infants, and children, the EJPS is an indispensable resource for all specialists.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信