Correlates of condom failure in a sexually active cohort of men who have sex with men.

E Stone, P Heagerty, E Vittinghoff, J M Douglas, B A Koblin, K H Mayer, C L Celum, M Gross, G E Woody, M Marmor, G R Seage, S P Buchbinder
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引用次数: 88

Abstract

Condom failure (slippage or breakage) has been shown to be associated with HIV seroconversion among men who have sex with men (MSM), but predictors of failure have been poorly elucidated. Of 2592 HIV-seronegative MSM participants in the HIV Network for Prevention Trials (HIVNET) multisite Vaccine Preparedness Study who reported condom use for anal sex in the 6 months before enrollment, condom failure was reported by 16.6%, with failure rates of 2.1/100 episodes of condom usage (2.5 failures/100 episodes for receptive anal sex and 1.9/100 episodes for insertive anal sex). In separate multivariate models evaluating predictors of condom failure reported by the insertive and receptive partners, more frequent condom use was associated with a decreased per-condom failure rate and amphetamine and heavy alcohol use with increased rates in both models. Being employed, having private medical insurance, and using lubricants for >80% of anal sex acts were significantly associated with decreased failure rates in the insertive model. Safer sex counseling should particularly target men of lower socioeconomic status, promote proper and consistent use of condoms with appropriate lubricants, and address the impact of drug use, especially amphetamines and alcohol, on condom failure.

性活跃的男男性群体中避孕套失效的相关因素。
避孕套失效(滑脱或破裂)已被证明与男男性行为者(MSM)的艾滋病毒血清转化有关,但失效的预测因素尚未得到充分阐明。在HIV预防试验网络(HIVNET)多站点疫苗准备研究中,2592名HIV血清阴性的男男性行为者在入组前6个月内报告肛交时使用安全套,安全套失效率为16.6%,安全套使用失败率为2.1/100次(接受性肛交为2.5 /100次,插入性肛交为1.9/100次)。在评估插入性伴侣和接受性伴侣报告的避孕套失效预测因素的单独多变量模型中,在两个模型中,更频繁地使用避孕套与每只避孕套失败率降低有关,而苯丙胺和大量酒精的使用与失败率增加有关。有工作,有私人医疗保险,在超过80%的肛交行为中使用润滑剂与插入模型中失败率的降低显著相关。安全性行为咨询应特别针对社会经济地位较低的男性,促进正确和一贯地使用带有适当润滑剂的避孕套,并解决吸毒,特别是安非他明和酒精对避孕套失效的影响。
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