{"title":"Structure and validation of a pharmacokinetic model for benzene.","authors":"G C Sinclair, C N Gray, R J Sherwood","doi":"10.1080/00028899908984444","DOIUrl":null,"url":null,"abstract":"<p><p>A pharmacokinetic model for benzene has been developed and validated for the inhalation aspects of its operation. The validation shows reasonable agreement between the model outputs and human biological data for phenol in urine, benzene in alveolar air, and benzene in mixed exhaled air.</p>","PeriodicalId":7930,"journal":{"name":"American Industrial Hygiene Association journal","volume":"60 2","pages":"249-58"},"PeriodicalIF":0.0000,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00028899908984444","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Industrial Hygiene Association journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/00028899908984444","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9
Abstract
A pharmacokinetic model for benzene has been developed and validated for the inhalation aspects of its operation. The validation shows reasonable agreement between the model outputs and human biological data for phenol in urine, benzene in alveolar air, and benzene in mixed exhaled air.
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