[Lipid peroxidation in chronic lead exposure].

Abstract

The state of lipid peroxidation, monitored by MDA concentration in the blood plasma of 46 battery workers with lead level in the blood in the 1.26-5.6 mol/l range is investigated. Higher MDA concentration (4.61 + 0.6) mol (ml in the blood plasma of exposed workers in comparison with the control sample of nonexposed workers is statistically established. The greater part of exposes workers (56.6%) have MDA concentration above the upper reference range. The significant correlation (r = +0.54) of the lipid peroxidation with the lead level in the blood is established. The investigation results show the rise of lipid peroxidation in workers chronically exposed to lead. This rise is more significant at lead levels above 1.92 mol/l.