[Deviations in the hematological indices of women exposed to aromatic hydrocarbons].

Problemi na khigienata Pub Date : 1997-01-01
V Khristeva-Mircheva, E Traĭkova
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Abstract

The indices of peripheral blood were investigated in 73 female laboratorians of the "Complex Laboratory for Analysis of Aromatic Carbohydrates", who were distributed into four groups according to the intensity of exposition. In the air of the laboratory medium the following substances were determined: benzene, toluen, xylols, ethylenic oxide, acrylnitril. The established concentrations were below or around the values of the mean maximum admissible concentrations (MMACV). Eleven indices of the three blood populations were followed up including white blood cell differential count and assessment of the activity of alkaline phosphatase in the polymorphonuclears. The same indices were investigated in 22 females, forming a control group. It was established that 26% of the examined female laboratorians were with anaemic syndrome, in 22.8% leucocytosis was present, while the alkaline phosphatase in the polymorphonuclears was with strongly inhibited activity. Although that on the bases of the formed 4 groups the dependencies "dose-response" and "dose-effect" were not established, the described deviations in the indices of the peripheral blood and expressed in a high percentage of the female laboratorians of the "Complex Laboratory for Analysis of Aromatic Carbohydrates" (CLAAC) direct to exerted effect by the occupational chemical harms upon the blood system of the examined females.

[接触芳香烃的妇女血液学指标的偏差]。
对“芳香碳水化合物分析综合实验室”73名女化验员的外周血指标进行了调查,按暴露强度分为4组。在实验室介质的空气中测定了下列物质:苯、甲苯、木醇、环氧乙烷、丙烯腈。确定的浓度低于或接近平均最大允许浓度(MMACV)值。对3个人群进行了白细胞差异计数和多形核碱性磷酸酶活性测定等11项指标的随访。选取22名女性作为对照组,进行相同指标的调查。发现26%的女性化验员有贫血综合征,22.8%的化验员有白细胞增多,多形核碱性磷酸酶活性强烈抑制。虽然在所形成的4组基础上没有建立起“剂量-反应”和“剂量-效应”的依赖关系,但在“芳香族碳水化合物综合分析实验室”(CLAAC)的女性实验室人员中,外周血指标的描述偏差和所表达的比例较高,直接说明职业化学危害对被测女性血液系统的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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