[An evaluation of the toxic exposure to inhalation anesthetics and disinfectants on liver function. II].

Abstract

The object of the study was evaluation of the functional state of the liver of surgeons and anaesthesiologists, exposed to halothane, paradise gas and disinfectants (formaldehyde). A representative group of 107 individuals was involved, distributed into two professional groups: surgeons (AcAT, AIAT, AP, gamma-GT) was determined. The analyses were performed on "Pointe 190", USA. Increased incidence and degree of deviations in the transaminases were established; a correlation between the results from the biochemical analyses and the toxicometric records. In conclusion the established correlations "dose-effect" and "dose-response" confirmed that the liver is a critical organ under the conditions of combined effect exerted by haolthane and paradise gas.