Development of a reference system for the international standardization of HbA1c/glycohemoglobin determinations.

W Hoelzel, K Miedema
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Abstract

The essential role of glycohemoglobin measurements in diabetes care and the currently poor comparability of results between different methods used in clinical laboratories makes an international standardization absolutely necessary. The IFCC working group on HbA1c standardization is going to develop a reference system for the international standardization which is based on HbA1c as the biochemically well-defined major glycohemoglobin component, and consisting of primary and secondary reference materials, a reference method and adjusted reference and target values. The system will serve for the standardization of all glycohemoglobin assays.

HbA1c/糖蛋白测定国际标准化参考系统的建立。
糖蛋白测量在糖尿病治疗中的重要作用,以及目前临床实验室使用的不同方法之间结果的可比性差,使得国际标准化是绝对必要的。IFCC糖化血红蛋白标准化工作组拟建立以糖化血红蛋白为生物化学定义明确的主要糖蛋白组分,由一级和二级标准物质、参考方法、调整后的参考值和目标值组成的国际标准化参考体系。该系统将用于所有糖蛋白测定的标准化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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