Towards safer drug use in general practice

ID Steven MD, MPH, FRACGP, A Malpass BHSc(Hons), J Moller BA, BSocAdmin, MPolAdmin, WB Runciman MBBCh, FANZCA, FFICANZCA, FRCA, FHKCA, PhD, SC Helps MSc, PhD
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引用次数: 31

Abstract A voluntary, anonymous incident-monitoring study was set up to identify and characterize events or circumstances which could have or did harm a patient in general practice. The study included 673 practitioners who made 2582 reports, of which half (n = 1294) involved medication problems. Amongst these reports, 1556 adverse drug events (ADE) were identified. More common in general practice than in hospitals were problems with therapeutic use (26% vs. 8%), and prescribing of contraindicated medications (15% vs. 5%). In the latter group, 64 reports (4%) involved the prescription of a medication to which the patient was known to be allergic, 66 (4%) involved medication for which there was a recognized potential for a drug interaction, and 68 (4%) involved contraindicated medications due to pathophysiological factors. It was estimated that computer-based prescribing with decision support could eliminate at least a third of these problems in general practice. Further studies are needed to develop this and other preventive strategies.

在一般实践中更安全地使用药物
摘要:一项自愿的、匿名的事件监测研究旨在识别和描述在一般实践中可能伤害或确实伤害患者的事件或情况。该研究包括673名从业人员,他们提交了2582份报告,其中一半(n = 1294)涉及药物问题。在这些报告中,确定了1556例药物不良事件(ADE)。在全科诊所比在医院更常见的是治疗使用问题(26%对8%)和处方禁忌症药物(15%对5%)。在后一组中,64例(4%)报告涉及患者已知过敏的药物处方,66例(4%)涉及已知可能发生药物相互作用的药物,68例(4%)涉及由于病理生理因素而禁忌的药物。据估计,有决策支持的计算机处方可以在一般实践中消除至少三分之一的这些问题。需要进一步的研究来制定这一战略和其他预防战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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