[Urodynamic studies in the diagnosis of infravesical obstruction in men].

Urologiia i nefrologiia Pub Date : 1998-11-01
S Kh Al'-Shukri, V N Tkachuk, A G Gorbachev, I V Kuz'min, R E Amdiĭ, V V Kozlov
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Abstract

The authors have performed urodynamic investigations pressure-flow in 39 males (mean age 57.9 +/- 1.8 years) to detect infravesical obstruction. Interpretation of the findings rested upon Abrams-Griffits index (AGI) derived by the formula AGI = PdetQmax - 2xQmax, where Qmax is the maximal speed of urine flow and PdetQmax is detrusor pressure when the maximal urine flow is reached. Definite conclusion on the presence or absence of infravesical obstruction was feasible for 21(53.8%) of 39 examinees, was not possible for 18(46.2%) patients. Statistical processing yielded non-linear relationship between PdetQmax and Qmax (cubic parabola) requiring correction for AGI (coefficient K calculated according to the formula K = 58.7 - 0.00554x(Qmax)3). This correction for nonlinearity K allowed classification of 11 out of 18 patients who were initially indefinite. By standard AGI technique, the uncertainty zone made up 46.2% while correction for nonlinearity reduced this zone to 18.0% (p < 0.008). Thus, the account for nonlinearity of the relationship between PdetQmax and Qmax may contribute to a rise in diagnostic value of urodynamic investigations.

【尿动力学在男性膀胱下梗阻诊断中的应用】。
作者对39名男性(平均年龄57.9±1.8岁)进行尿动力学压力流检查,以检测膀胱下梗阻。对研究结果的解释基于Abrams-Griffits指数(AGI),该指数由公式AGI = PdetQmax - 2xQmax推导而来,其中Qmax为最大尿流速度,PdetQmax为达到最大尿流时的逼尿肌压力。39例患者中有21例(53.8%)能明确判断有无膀胱下梗阻,18例(46.2%)不能确定。统计处理得出PdetQmax和Qmax(三次抛物线)之间存在非线性关系,需要对AGI进行校正(系数K根据公式K = 58.7 - 0.00554x(Qmax)3计算)。对非线性K的校正允许对最初不确定的18例患者中的11例进行分类。通过标准AGI技术,不确定性区域占46.2%,而非线性校正将该区域减少到18.0% (p < 0.008)。因此,考虑到PdetQmax和Qmax之间关系的非线性可能有助于提高尿动力学检查的诊断价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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