[Changes in the levels of prostate-specific antigen and its molecular forms with alpha 1-antichymotrypsin in patients with benign prostatic hyperplasia].

Urologiia i nefrologiia Pub Date : 1998-07-01
M E Grigor'ev, E B Mazo, V P Chekhonin
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引用次数: 0

Abstract

Analysis of the changes in the levels of total prostatic specific antigen (t-PSA) in patients with benign prostatic hyperplasia (BPH) shows that the patient's age, size of the prostatic gland and chronic bacterial prostatitis influence the levels of t-PSA but have no effect on the levels of PSA-ACT. The relationship between the levels of t-PSA and age in BPH patients is explained by growing mass of benign hyperplasia causing mechanical load on the intact prostatic tissue. The maximal concentration of t-PSA of 8.7 +/- 1.22 ng/ml was observed in BPH patients at the age of 61-70 years. BPH stages, chronic pyelonephritis, chronic non-bacterial prostatitis, chronic renal failure are not essential for t-PSA and PSA-ACT and can be neglected in interpretation of t-PSA values in BPH patients.

[前列腺增生患者前列腺特异性抗原及其分子形态与α - 1抗凝乳胰蛋白酶水平的变化]。
对良性前列腺增生(BPH)患者总前列腺特异性抗原(t-PSA)水平变化的分析表明,患者年龄、前列腺大小和慢性细菌性前列腺炎对t-PSA水平有影响,但对PSA-ACT水平无影响。前列腺增生患者的t-PSA水平与年龄之间的关系可以通过良性增生的增多对完整的前列腺组织造成机械负荷来解释。在61 ~ 70岁的BPH患者中,t-PSA的最大浓度为8.7 +/- 1.22 ng/ml。BPH分期、慢性肾盂肾炎、慢性非细菌性前列腺炎、慢性肾衰竭对t-PSA和PSA-ACT不是必需的,在解释BPH患者的t-PSA值时可以忽略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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