[Gonarthrosis--current aspects of therapy with glucosamine sulfate (dona200-S)].

Abstract

For many years glucosamine sulfate has been successfully used in the therapy of osteoarthritis. Today's importance of the treatment with glucosamine sulfate is even increasing. Glucosamine sulfate meets all standards of an efficient and well tolerated drug. This is proven by experimental as well as clinical studies, in which glucosamine sulfate was tested in accordance with the current state of scientific research. The results show that glucosamine sulfate will lead to long-lasting pain reduction and functional improvement by means of increasing anabolical mechanisms, reducing the activity of proteolytic enzymes and by its antiinflammatory effect. Since this therapeutical effect is not due to an inhibition of the prostaglandin synthesis, treatment is not accompanied by the known unwanted side effects. Glucosamine sulfate is very well tolerated by patients of all ages under short-term as well as long-term treatment.