Joel P Schneider , Angela Lombardi , William F DeGrado
{"title":"Analysis and design of three-stranded coiled coils and three-helix bundles","authors":"Joel P Schneider , Angela Lombardi , William F DeGrado","doi":"10.1016/S1359-0278(98)00011-X","DOIUrl":null,"url":null,"abstract":"<div><p>Three-stranded coiled coils and three-helix bundles are increasingly being identified in proteins. Design and engineering on the scaffolds of these motifs is a potential route towards combating associated viral infections as well as introducing novel functional sites.</p></div>","PeriodicalId":79488,"journal":{"name":"Folding & design","volume":"3 2","pages":"Pages R29-R40"},"PeriodicalIF":0.0000,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1359-0278(98)00011-X","citationCount":"47","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folding & design","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S135902789800011X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 47
Abstract
Three-stranded coiled coils and three-helix bundles are increasingly being identified in proteins. Design and engineering on the scaffolds of these motifs is a potential route towards combating associated viral infections as well as introducing novel functional sites.