Evaluation of culture, histological examination, serology and the rapid urease test for diagnosis of Helicobacter pylori in patients with dyspepsia in Bangladesh.

Japanese journal of medical science & biology Pub Date : 1997-04-01 DOI:10.7883/yoken1952.50.55

M G Morshed, F Jinnah, M S Islam, M A Rumi, S Ahmed, M M Ahmed, M Sadeque, M F Chowdhury

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引用次数: 8

Abstract

Helicobacter pylori, a gram-negative, microaerophilic bacterium, has been established to have a causal association with chronic gastritis, peptic ulcer, gastric adenocarcinoma, and low-grade lymphoma. The present study was undertaken to evaluate the efficacy of culture, histological examination, the rapid urease test, and serology for the diagnosis of H. pylori infection. A total of 45 consecutive subjects with various upper gastrointestinal symptoms were included in this study. The rates of diagnosis of H. pylori infection were 51.1%, 55.6%, 82.2%, and 93.3%, by culture, rapid urease test (RUT), histological examination, and serology, respectively. The sensitivity, specificity, and positive and negative predictive values were 95.5%, 82.6%, 84.0%, and 95.0%, respectively for RUT; 95.5%, 30.4%, 56.8%, and 87.5% for histological examination; 100%, 13.6%, 54.8% and 100% for serology.

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孟加拉国消化不良患者幽门螺杆菌培养、组织学检查、血清学和快速脲酶试验诊断的评价

幽门螺杆菌是一种革兰氏阴性的嗜微气细菌，已被证实与慢性胃炎、消化性溃疡、胃腺癌和低度淋巴瘤有因果关系。本研究旨在评估培养、组织学检查、快速脲酶试验和血清学对幽门螺杆菌感染诊断的有效性。本研究共纳入45名连续出现各种上消化道症状的受试者。通过培养、快速脲酶试验(RUT)、组织学检查和血清学检查，幽门螺杆菌感染的诊断率分别为51.1%、55.6%、82.2%和93.3%。RUT的敏感性为95.5%，特异性为82.6%，阳性预测值84.0%，阴性预测值95.0%;组织学检查95.5%、30.4%、56.8%、87.5%;血清学为100%，13.6%，54.8%，100%。

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Japanese journal of medical science & biology

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