Dietary controls produce positive results for a non-insulin-dependent diabetes mellitus patient.

L I Silverberg, S Eng
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Abstract

Renal disease is a leading cause of death and disability for diabetic patients. Diabetic nephropathy is responsible for half of the cases of end-stage renal disease in the United States. For non-insulin-dependent diabetes mellitus patients, the prevalence of diabetic nephropathy varies from 15% to 60% and is influenced by genetic background. Early screening and controlling of microalbumin levels are essential to affect the outcome of diabetic nephropathy. Studies show that clinical renal dysfunction in diabetics does not correlate well with the histological abnormalities. Strategies for nephropreservation include close lipid, glycemic, and blood pressure control, and tobacco termination. Use of angiotensin-converting enzyme inhibitors exert nephroprotective effects beyond their beneficial blood pressure-lowering effects. The importance of strict diet is emphasized in a case presentation.

饮食控制对非胰岛素依赖型糖尿病患者产生阳性结果。
肾脏疾病是糖尿病患者死亡和残疾的主要原因。糖尿病肾病是负责一半的终末期肾脏疾病在美国。对于非胰岛素依赖型糖尿病患者,糖尿病肾病的患病率从15%到60%不等,并受遗传背景的影响。早期筛查和控制微量白蛋白水平对影响糖尿病肾病的预后至关重要。研究表明,糖尿病患者的临床肾功能不全与组织学异常没有很好的相关性。肾保护的策略包括密切控制血脂、血糖和血压,以及戒烟。血管紧张素转换酶抑制剂的使用除了其有益的降血压作用外,还具有肾保护作用。在一个案例介绍中强调了严格饮食的重要性。
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