{"title":"Chromatin and ageing in yeast and in mammals.","authors":"L Guarente","doi":"10.1002/9780470515433.ch7","DOIUrl":null,"url":null,"abstract":"<p><p>Genetic studies have identified genes that appear to regulate the pace of ageing in model systems and in humans. The molecular analysis of these genes will provide insight into causes of ageing. Here I discuss recent findings in yeast that suggest possible mechanisms of ageing and relate them to the disease of Werner's syndrome, which causes symptoms of premature ageing in humans.</p>","PeriodicalId":10218,"journal":{"name":"Ciba Foundation symposium","volume":"211 ","pages":"104-7; discussion 107-11"},"PeriodicalIF":0.0000,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/9780470515433.ch7","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ciba Foundation symposium","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/9780470515433.ch7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
Genetic studies have identified genes that appear to regulate the pace of ageing in model systems and in humans. The molecular analysis of these genes will provide insight into causes of ageing. Here I discuss recent findings in yeast that suggest possible mechanisms of ageing and relate them to the disease of Werner's syndrome, which causes symptoms of premature ageing in humans.
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