Modeling Obesity Using Abductive Networks

R.E. Abdel-Aal , A.M. Mangoud
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引用次数: 19

Abstract

This paper investigates the use of abductive-network machine learning for modeling and predicting outcome parameters in terms of input parameters in medical survey data. Here we consider modeling obesity as represented by the waist-to-hip ratio (WHR) risk factor to investigate the influence of various parameters. The same approach would be useful in predicting values of clinical parameters that are difficult or expensive to measure from others that are more readily available. The AIM abductive network machine learning tool was used to model the WHR from 13 other health parameters. Survey data were collected for a randomly selected sample of 1100 persons aged 20 yr and over attending nine primary health care centers at Al-Khobar, Saudi Arabia. Models were synthesized by training on a randomly selected set of 800 cases, using both continuous and categorical representations of the parameters, and evaluated by predicting the WHR value for the remaining 300 cases. Models for WHR as a continuous variable predict the actual values within an error of 7.5% at the 90% confidence limits. Categorical models predict the correct logical value of WHR with an error in only 2 of the 300 evaluation cases. Analytical relationships derived from simple categorical models explain global observations on the total survey population to an accuracy as high as 99%. Simple continuous models represented as analytical functions highlight global relationships and trends. Results confirm the strong correlation between WHR and diastolic blood pressure, cholesterol level, and family history of obesity. Compared to other statistical and neural network approaches, AIM abductive networks provide faster and more automated model synthesis. A review is given of other areas where the proposed modeling approach can be useful in clinical practice.

利用溯因网络建模肥胖
本文研究了利用溯因网络机器学习对医学调查数据中的输入参数进行建模和预测结果参数的方法。在这里,我们考虑以腰臀比(WHR)风险因子为代表的肥胖建模,以研究各种参数的影响。同样的方法在预测临床参数值时也很有用,这些参数很难或昂贵地从其他更容易获得的参数中测量出来。使用AIM溯因网络机器学习工具从13个其他健康参数对WHR进行建模。收集了随机抽取的在沙特阿拉伯霍巴尔市9个初级卫生保健中心就诊的1100名20岁及以上的人的调查数据。通过对随机选择的800个案例进行训练,使用参数的连续和分类表示来合成模型,并通过预测剩余300个案例的WHR值来评估模型。将WHR作为连续变量的模型在90%置信限下预测实际值的误差为7.5%。在300个评估案例中,分类模型预测WHR的正确逻辑值只有2个有错误。从简单分类模型中得出的分析关系解释了对总调查人口的全球观测结果,准确率高达99%。用分析函数表示的简单连续模型强调全局关系和趋势。结果证实腰宽比与舒张压、胆固醇水平和肥胖家族史之间有很强的相关性。与其他统计和神经网络方法相比,AIM溯因网络提供了更快、更自动化的模型合成。回顾了其他领域,其中提出的建模方法可以在临床实践中有用。
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