Regional differences in long-term mortality among hospital-treated asthma and COPD patients.

T Tuuponen, T Keistinen, S L Kivelä
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引用次数: 3

Abstract

Chronic obstructive pulmonary diseases, which have increased due to smoking and ageing of the population, constitute a national health problem, the treatment of which can be expected to arouse considerable discussion in health care organisations currently preoccupied with economic problems. Although extensive medication and easy access to treatment are often regarded as therapeutically desirable, it may be questioned whether they have any impact on objective measures such as mortality. International recommendations for the early treatment of asthma have met with satisfaction and the asthma situation can be said to be under control, even though occurrences tend to be on the increase. It should be noted, however, that the COPD treatment recommendations still remain to be tested and the general attitude towards treatment is still reserved, even pessimistic. By combining data from the Finnish national hospital discharge register and register of deaths with findings regarding the use of medications, differences in the survival of asthmatic and COPD patients can be discerned between areas with different treatment practices. Stressing the fact that effect-differences between different treatment strategies can not be proven on the basis register data and that random clinical trials are needed to gain further knowledge in the field, our results show that extensive medication and easy access to treatment are characteristic of areas where the survival of asthmatics and COPD patients is better.
住院治疗哮喘和慢性阻塞性肺病患者长期死亡率的地区差异
慢性阻塞性肺病由于吸烟和人口老龄化而增加,构成了一个全国性的健康问题,预计其治疗将在目前专注于经济问题的卫生保健组织中引起大量讨论。虽然广泛的药物治疗和容易获得治疗通常被认为是治疗上的可取之处,但它们是否对死亡率等客观指标有任何影响可能会受到质疑。国际上关于早期治疗哮喘的建议取得了令人满意的效果,哮喘的情况可以说得到了控制,尽管发病率有增加的趋势。然而,值得注意的是,COPD的治疗建议仍有待检验,对治疗的普遍态度仍然是保留的,甚至是悲观的。通过将芬兰国家医院出院登记和死亡登记的数据与有关药物使用的调查结果相结合,可以区分不同治疗方法地区哮喘和慢性阻塞性肺病患者的生存差异。强调不同治疗策略之间的效果差异不能根据注册数据证明,需要随机临床试验来获得该领域的进一步知识,我们的研究结果表明,广泛的药物治疗和容易获得的治疗是哮喘和COPD患者生存更好的地区的特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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