[Surgical treatment and long-term results of congenital heart disease in adults: early and late follow-up studies in 231 cases].

T Abe, K Kamata, A Taguchi, S Sugimoto, T Kawashima, S Inoue, K Nakanishi, N Takahashi, M Morikawa, A Sasaki
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Abstract

In a past one decade from January 1981 to August 1991, 231 patients over 18 years old with congenital heart disease (CHD) including 65 patients with cyanotic (C) and 166 with acyanotic (AC) diseases, were surgically treated. There were one operative death (0.6 percent mortality) and three late deaths (1.9%) in 166 patients with AC diseases, whereas there were four operative (6.1%), and four late deaths (6.1%) in 65 patients with C. These patients were followed for 3 to 124 months (the mean of 46.4 +/- 11.9) after the operation. Compared with group AC, group C showed a high rate of early postoperative deaths or late deaths. Group AC comprised patients in their forties (95 patients with ASD and 15 with PDA) and those in their thirties (26 with VSD and 13 with ECD) at the operation. On the contrary, except 5 patients with Ebstein disease, a mean age of patients of group C at the operation lay in their twenties. Surgical outcomes for adult patients of group C still pose much problems compared with AC group in terms of decreased heart function, development of collateral circulatory pathway, and impaired hepatic and renal functions by long lasting hypoxemia. In group C decreased heart function or association of abscess of the brain might be the main cause of postoperative LOS. These findings indicate that early diagnosis, recent advanced operative procedure and appropriate postoperative care can provide symptomatic remission for even adult patients with severe CHD with a low mortality.

[成人先天性心脏病的手术治疗和长期结果:231例早期和晚期随访研究]。
在1981年1月至1991年8月的十年间,对231例18岁以上的先天性心脏病(CHD)患者进行了手术治疗,其中紫绀型(C) 65例,无绀型(AC) 166例。166例AC患者有1例手术死亡(死亡率为0.6%),3例晚期死亡(死亡率为1.9%),而65例c患者有4例手术死亡(6.1%),4例晚期死亡(6.1%)。这些患者术后随访3 ~ 124个月(平均46.4±11.9)。与AC组比较,C组术后早期死亡率和晚期死亡率较高。AC组由40多岁(ASD 95例,PDA 15例)和30多岁(VSD 26例,ECD 13例)的患者组成。相反,除5例Ebstein病外,C组患者手术时的平均年龄为20多岁。与AC组相比,C组成年患者的手术结局在心功能下降、侧支循环通路发育、长期低氧血症导致肝肾功能受损等方面仍存在诸多问题。C组心功能下降或伴有脑脓肿可能是术后LOS的主要原因。这些发现表明,早期诊断、近期的先进手术和适当的术后护理可以使死亡率低的成年重症冠心病患者症状缓解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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