X-ray phototherapy for canine brain masses.

A Norman, M Ingram, R G Skillen, D B Freshwater, K S Iwamoto, T Solberg
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引用次数: 71

Abstract

Brain masses diagnosed in 47 pet dogs as tumors by CT scans, and confirmed in 12 dogs by necropsies, were injected with iodinated contrast media and treated by a modified CT scanner, the CTRx. Twenty-six dogs that received six or more weekly treatments of about 5.6 Gy per fraction, of which about 25% was contributed by radiation from the iodine, for a median total dose of 39 Gy, had a median survival of 230 days. This compares well with the 150 days reported for 25 dogs given 46-48 Gy of cobalt-60 radiation to the whole brain, and is significantly greater than the 6 to 13 days in untreated historic controls.

犬脑肿块的x射线光疗。
47只宠物狗的脑部肿块经CT扫描诊断为肿瘤,12只狗经尸检证实为肿瘤。研究人员给它们注射了碘化造影剂,并用改良的CT扫描仪CTRx进行治疗。26只狗每周接受6次或更多的治疗,每次治疗剂量约为5.6 Gy,其中约25%是由碘辐射造成的,中位总剂量为39 Gy,平均存活时间为230天。这与25只狗接受46-48 Gy钴-60全脑辐射的150天相比要好得多,并且明显大于未治疗的历史对照组的6- 13天。
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