Robert P. Kraus M.D., F.R.C.P.(c)
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引用次数: 8
Abstract
A treatment-resistant depressed patient developed bipolar rapid cycling in response to pindolol augmentation of paroxetine, after failing to respond in any fashion to pindolol added to desipramine. The rapid cycling initially faded, but recurred after the pindolol dose was increased (in combination with paroxetine) in an attempt to treat a relapse into depression. Her differential development of rapid cycling with pindolol in combination with the SSRI is in keeping with the theory that pindolol augmentation operates via a serotonergic mechanism. Depression 4:92–94 (1996). © 1997 Wiley-Liss, Inc.
匹多洛尔增加帕罗西汀可触发快速循环，但地西帕明不会
一名治疗难治性抑郁症患者在对去西帕明加品多洛没有任何反应后，在帕罗西汀加品多洛后出现双相快速循环。快速循环最初消退，但在增加品多洛尔剂量(与帕罗西汀联合使用)以治疗抑郁症复发后复发。pindolol联合SSRI快速循环的差异发展与pindolol增强通过血清素能机制起作用的理论一致。抑郁症:92 - 94(1996)。©1997 Wiley-Liss, Inc
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