Amyloid Precursor Protein mRNAs in Alzheimer's Disease

Paul J. Harrison , Wendy H. Wighton-Benn , Josephine M. Heffernan , Maurice W. Sanders , R.Carl A. Pearson
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引用次数: 11

Abstract

Hybridization studies of mRNA link genetic with neurochemical and neuropathological approaches to Alzheimer's disease (AD). Here we review the distribution and abundance of amyloid precursor protein mRNAs in normal and AD-afflicted brains. The expression of apolipoprotein E and presenilin mRNAs are also discussed.

阿尔茨海默病中的淀粉样前体蛋白mrna
阿尔茨海默病(AD)的遗传与神经化学和神经病理学途径的mRNA杂交研究。在这里,我们回顾了淀粉样蛋白前体蛋白mrna在正常和ad患者大脑中的分布和丰度。载脂蛋白E和早老素mrna的表达也进行了讨论。
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