A retrospective study of clinical characteristics of acinetobacter bacteremia.

T K Ng, J M Ling, A F Cheng, S R Norrby
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Abstract

High rates of acinetobacter bacteremia were observed in a large teaching hospital in Hong Kong. A retrospective study of 94 acinetobacter bacteremic episodes in patients in 1993-94 revealed 70 episodes of significant bacteremia. 53% of the patients were over 60 years with a male to female ratio of 1.5:1. Cases were most rare during the fourth quarter. The intensive care unit was the commonest location of acquisition of bacteremia. Most infections were hospital acquired. Intravascular catheters, urinary catheters, antibiotic therapy and respiratory tract manipulations were common risk factors. Lower respiratory tract infections and catheter-related sepsis were predominant foci of bacteremia. One-third of the patients received appropriate antibiotics within 48 hours after bacteremia onset. Mortality attributable to acinetobacter infection was 27%. Prognosis of underlying diseases, location in intensive care unit, lower respiratory tract infection as foci of infection as well as diabetes mellitus were associated with mortality.

不动杆菌菌血症临床特点的回顾性研究。
香港某大型教学医院的不动杆菌菌血症发生率较高。对1993- 1994年间94例不动杆菌菌血症患者的回顾性研究显示,有70例明显的菌血症。60岁以上的患者占53%,男女比例为1.5:1。第四季度的病例最为罕见。重症监护病房是获得菌血症最常见的地点。大多数感染是医院获得的。血管内导尿管、导尿管、抗生素治疗和呼吸道操作是常见的危险因素。下呼吸道感染和导管相关性脓毒症是主要的菌血症灶。三分之一的患者在菌血症发生后48小时内接受了适当的抗生素治疗。不动杆菌感染导致的死亡率为27%。基础疾病的预后、重症监护病房的位置、感染灶为下呼吸道感染以及糖尿病与死亡率相关。
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