[The participation of different types of opiate receptors in the mechanism of cardiac stressor damage].

Abstract

The immobilisation stress was shown to induce a heart lesion. The agonist of peripheral mu-receptors DALDA was able to prevent the lesion, and natrexone--to diminish the stressor effect. Activation of the central mu-receptors seems to potentiate the stressor damaging effect, whereas activation of peripheral mu-receptors prevents the heart lesions.