[The effect of phenol on the ion currents of the frog motor nerve ending].

Abstract

Phenol was shown to enhance the quantum content of the end-plate currents and to increase the duration of the nerve ending response. The effect could be abolished by the potassium channel blockers. The data obtained suggest that alteration of the kinetics of the potential-dependent potassium current of the nerve terminal is one of the mechanisms of the phenol facilitating effect on neuro-muscular transmission.