{"title":"[Determination of crude drugs in the pharmacopoeia].","authors":"H Suzuki, M Satake","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The determination of crude drugs by high performance liquid chromatograph (HPLC) method was introduced to the Japanese Pharmacopoeia (JP) 12 for the first time. At JP 13, another HPLC methods were established for eight kinds of crude drugs and relative medicines. Special conception is used in the determination of crude drugs, different from chemical medicines. Determinations were classified to two methods: \"assay\" and \"component determination\" according to standards. \"The Japanese Reference Standard\" or \"Reagent for assay\" is used in assay, and \"Reagent for component determination\". is used in component determination. In addition, the analysis and the dryness of crude drug were discussed because they were important to evaluate the result of analysis exactly.</p>","PeriodicalId":11656,"journal":{"name":"Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The determination of crude drugs by high performance liquid chromatograph (HPLC) method was introduced to the Japanese Pharmacopoeia (JP) 12 for the first time. At JP 13, another HPLC methods were established for eight kinds of crude drugs and relative medicines. Special conception is used in the determination of crude drugs, different from chemical medicines. Determinations were classified to two methods: "assay" and "component determination" according to standards. "The Japanese Reference Standard" or "Reagent for assay" is used in assay, and "Reagent for component determination". is used in component determination. In addition, the analysis and the dryness of crude drug were discussed because they were important to evaluate the result of analysis exactly.
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