Plasma vitamin A, zinc and selenium concentrations in children with acute and persistent diarrhoea.

S Chaudhary, M Verma, V Dhawan, C K Nain, R Kumar, L Kumar, N K Ganguly
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Abstract

Plasma zinc, selenium, and vitamin A concentrations in 25 children with persistent diarrhoea (PD) and acute diarrhoea (AD) were determined and compared with 25 age-matched control children. Plasma retinol concentrations (PRC) and plasma zinc concentrations (PZC) (3.92 micrograms/dL and 79.4 micrograms/dL respectively) were found to be significantly lower (p < 0.05) in children with PD. PZCs were also significantly reduced (p < 0.05) in children with AD. However, reduction in PZC was more in PD than that in AD. There was no significant difference in PSC in children with either types of diarrhoea as compared with the control group. The results of the study showed that there was deficiency of vitamin A and zinc in diarrhoeas which needs to be correlated for proper nutritional management.

急性和持续性腹泻患儿血浆维生素A、锌和硒浓度
测定了25例持续性腹泻(PD)和急性腹泻(AD)患儿的血浆锌、硒和维生素A浓度,并与25例年龄匹配的对照儿童进行了比较。血浆视黄醇浓度(PRC)和血浆锌浓度(PZC)(分别为3.92微克/分升和79.4微克/分升)显著低于PD患儿(p < 0.05)。AD患儿PZCs也显著降低(p < 0.05)。然而,PD患者PZC的减少比AD患者更多。与对照组相比,两种类型腹泻患儿的PSC均无显著差异。研究结果表明,腹泻中存在维生素A和锌的缺乏,这需要与适当的营养管理相关联。
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