B Regland, B V Johansson, B Grenfeldt, L T Hjelmgren, M Medhus
{"title":"Homocysteinemia is a common feature of schizophrenia.","authors":"B Regland, B V Johansson, B Grenfeldt, L T Hjelmgren, M Medhus","doi":"10.1007/BF01271539","DOIUrl":null,"url":null,"abstract":"<p><p>A significant proportion of patients with schizophrenia have increased homocysteine levels that are unrelated to psychopharmacological medication or nutrient deficiency in folate or cobalamin. This supports the hypothesis that inherent methylation deficiency is involved in the pathogenesis of schizophrenia.</p>","PeriodicalId":77215,"journal":{"name":"Journal of neural transmission. General section","volume":"100 2","pages":"165-9"},"PeriodicalIF":0.0000,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF01271539","citationCount":"96","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of neural transmission. General section","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF01271539","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 96
Abstract
A significant proportion of patients with schizophrenia have increased homocysteine levels that are unrelated to psychopharmacological medication or nutrient deficiency in folate or cobalamin. This supports the hypothesis that inherent methylation deficiency is involved in the pathogenesis of schizophrenia.