The association between tumour necrosis factor-alpha, interleukin-6 and microbiological findings in the synovial fluid of aborted and neonatal calves.

R Meirom, S Moss, M Bernstein, Z Bider, J Brenner
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引用次数: 2

Abstract

Tumour necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) were detected in the intra-carpal synovial fluids collected from aborted and recently dead young calves. Five out of seven TNF-alpha positive joint fluids were bacteriologically positive and two were sterile. Only one out of 20 TNF-alpha negative joint aspirates was infected (P = 0.0014). Sixteen of the synovial fluid samples were examined for the presence of IL-6. In 12 samples IL-6 was detected, six of which were bacteriologically contaminated. Four out of the 16 samples were IL-6 negative. These findings indicated the possible association between TNF-alpha and the intra-articular inflammatory processes in young calves, which in the present study were either found in combination with or without IL-6.

肿瘤坏死因子- α、白细胞介素-6和微生物在流产和新生牛犊滑液中的发现之间的关系。
肿瘤坏死因子- α (TNF - α)和白细胞介素-6 (IL-6)在从流产和最近死亡的幼犊收集的腕内滑液中检测。7例tnf - α阳性关节液中有5例细菌学阳性,2例无菌。20例tnf - α阴性关节抽吸者中仅有1例感染(P = 0.0014)。16个滑液样本检查IL-6的存在。在12份样本中检测到IL-6,其中6份被细菌污染。16例样本中有4例IL-6阴性。这些发现表明,tnf - α与幼犊关节内炎症过程之间可能存在关联,在本研究中,tnf - α与IL-6或不与IL-6联合发现。
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