Dietary intervention in a hypercholesterolemic school-aged population from Northern Spain.

Revista espanola de fisiologia Pub Date : 1996-03-01
A García, J M Gutiérrez, S Fernández, J Aparicio, A Menéndez-Patterson
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Abstract

A "before and after" intervention study, over a five year period, was done in order to find the degree of compliance to dietary recommendations and their effects on serum lipids in a hypercholesterolemic school-aged population. 383 children between 6 and 13 years of age, were identified with hypercholesterolemia (total serum levels above 4.8 mmol/l), in a previous randomized mass screening of 1095 individuals. Some dietary guidelines aimed at decreasing fat consumption and increasing fiber and carbohydrate ingestion were given to the families, and 226 of the children participated in the follow-up. Changes of address and/or school-center was the main cause of non-participation. The follow-up examination consisted in the evaluation of serum lipids and actual diet. Cholesterol serum levels decreased from a mean value of 5.4 mmol/l to 4.8 mmol/l. 59.3% of the sample had reached serum cholesterol levels below the risk threshold. Fat ingestion diminished significantly (40.3% of calories to 36.7%, p < 0.001), saturated fatty acids decreased from 15.3% of calories to 13.5% (p < 0.001), monounsaturated fatty acids decreased from 17.1% to 15.4% (p < 0.001) and polyunsaturated fatty acids remained unchanged. Carbohydrate consumption increased from 45% of the calories to 47.38% (p < 0.001). Dietary changes were greater in individuals out of risk than those who still had high cholesterol levels. These data indicate a good family compliance to the recommendations and that changes in food habits seem to be effective in controlling hyperlipidemia. Dietary changes are better accepted by younger children.

西班牙北部高胆固醇学龄人群的饮食干预
一项为期五年的“前后”干预研究,旨在发现高胆固醇学龄人群对饮食建议的遵守程度及其对血脂的影响。在之前的1095例随机筛查中,383名6至13岁的儿童被确诊为高胆固醇血症(血清总水平高于4.8 mmol/l)。研究人员给这些家庭提供了一些旨在减少脂肪摄入、增加纤维和碳水化合物摄入的膳食指南,其中226名儿童参与了随访。地址及/或学校中心的变动是不参与的主要原因。随访检查包括评估血脂和实际饮食。血清胆固醇水平从平均值5.4 mmol/l降至4.8 mmol/l。59.3%的样本血清胆固醇水平低于危险阈值。脂肪摄入显著减少(热量的40.3%降至36.7%,p < 0.001),饱和脂肪酸从15.3%降至13.5% (p < 0.001),单不饱和脂肪酸从17.1%降至15.4% (p < 0.001),多不饱和脂肪酸保持不变。碳水化合物的摄入量从卡路里的45%增加到47.38% (p < 0.001)。与那些胆固醇水平仍然很高的人相比,没有风险的人的饮食变化更大。这些数据表明,一个家庭很好地遵守了这些建议,改变饮食习惯似乎对控制高脂血症有效。年幼的孩子更容易接受饮食的改变。
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