[Prevention of postoperative nausea and vomiting by lorazepam].

Cahiers d'anesthesiologie Pub Date : 1996-01-01
M Laraki, M el Mouknia, A Bouaguad, B Idali, M Benaguida
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引用次数: 0

Abstract

This study was carried out to assess the efficacy of oral lorazepam on postoperative nausea and vomiting in patients undergoing thyroid surgery. Twenty-six patients were randomly assigned to two groups, and receiving orally, one hour before induction of anaesthesia, either 2.5 mg of lorazepam (n = 13) or a placebo (n = 13). Lorazepam reduced the incidence and especially the intensity of nausea. The incidence of vomiting in the lorazepam group was significantly lower than in the placebo group (14.5% vs 45%). The use of lorazepam for premedication thus reduces the incidence of postoperative nausea and vomiting. The advantages of this benzodiazepine are its ease of use, low cost and very low incidence of side effects.

[劳拉西泮预防术后恶心呕吐]。
本研究旨在评估口服劳拉西泮对甲状腺手术患者术后恶心和呕吐的疗效。26例患者随机分为两组,在麻醉诱导前1小时口服2.5 mg劳拉西泮(n = 13)或安慰剂(n = 13)。劳拉西泮减少了恶心的发生率,尤其是恶心的强度。劳拉西泮组呕吐发生率显著低于安慰剂组(14.5% vs 45%)。用药前使用劳拉西泮可减少术后恶心和呕吐的发生率。这种苯二氮卓类药物的优点是使用方便,成本低,副作用发生率极低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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