[Activity of alpha 1-antitrypsin in blood of patients operated on for tumor and benign hyperplasia of the prostate].

Z Zietek, I Iwan-Zietek, M Kotschy, F Tyloch
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Abstract

The activity of alpha 1-antitrypsin in the blood of the patients with prostatic carcinoma and benign prostatic hyperplasia before and after the operation was examined. It was observed an increase of alpha 1-antitrypsin in the blood of patients with prostatic carcinoma and benign prostatic hyperplasia after the operation. In the blood patients of control group an increase of alpha 1-antitrypsin was observed too. The activity of alpha 1-antitrypsin in prostatic carcinoma was the highest during the whole observation period. The similar increase of the activity of alpha 1-antitrypsin after the operation in the blood of all groups of patients is connected with inflammatory reaction. The highest activity of alpha 1-antitrypsin in the blood of patients with prostatic carcinoma is the proof that the malignant neoplasm is associated with much more inflammatory reaction and the further hormonal treatment can be connected with a risk of thromboembolic complications.

[前列腺肿瘤及良性增生手术患者血液α 1-抗胰蛋白酶的活性]。
检测前列腺癌及良性前列腺增生患者手术前后血液α 1-抗胰蛋白酶的活性。前列腺癌及良性前列腺增生患者术后血α 1-抗胰蛋白酶升高。对照组患者血液中α 1-抗胰蛋白酶水平也升高。α 1-抗胰蛋白酶在前列腺癌组织中的活性在整个观察期内均最高。各组患者术后血液α - 1-抗胰蛋白酶活性均出现相似的升高,与炎症反应有关。前列腺癌患者血液中α - 1-抗胰蛋白酶活性最高,这证明恶性肿瘤与更多的炎症反应有关,进一步的激素治疗可能与血栓栓塞并发症的风险有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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