[Radioimmunological determination of glucagon in Bulgarian insulin substances].

Abstract

The contents of glucagon in insulin substances ("Pharmachim" Ltd.) is determined in accordance to the needs of pharmaceutical production. The middle quantitative values and standart deviation are specified. Nevertheless that monocomponent and bovine conventional insulin substances pertain to groups of different purity they exibit the highest purity. Bovine conventional insulins exibit the greatest variability, while monocomponent insulins are destinctively homogenous. Single-peak insulin substances exhibit less purity, but this group is more homogenous. The middle quantitative value is within the admissible limitations. Porcine conventional insulins have high contents of glucagon as well as high values of standard deviation.