Spontaneous micronuclei in peripheral blood erythrocytes from 35 mammalian species

Mutation Research/Genetic Toxicology Pub Date : 1996-07-10 DOI:10.1016/S0165-1218(96)90056-7

G. Zúñiga , O. Torres-Bungarín , M.P. Ramírez-Muñoz , A. Ramos , E. Fanti-Rodríguez , E. Portilla , D. García-Martínez , J.M. Cantú , M.P. Gallegos-Arreola , J. Sánchez-Corona

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引用次数: 48

Abstract

In this paper we report the results of a study to determine the frequencies of spontaneous micronucleated erythrocytes (MNE) in peripheral blood of 35 mammalian species. The main goal was to find mammals with a high spontaneous frequency of MNE that could, therefore, be good candidates for biomonitoring genotoxic agents in their natural habitat. We obtained 187 peripheral blood samples, but in 13 of the species we could only sample one individual. A wide range in the number of MNE ( $1434 to 0 40 000$ erythrocytes) was observed. Since the number of individuals per species is not high enough, this results should be cautiously considered. The cat, mouse, giraffe, pig, opossum and capuchin monkey seem to be suitable species for biomonitoring for genotoxic events.

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35种哺乳动物外周血红细胞的自发微核

本文报道了一项测定35种哺乳动物外周血中自发微核红细胞(MNE)频率的研究结果。研究的主要目标是寻找具有高自发性MNE频率的哺乳动物，因此，这些哺乳动物可能是在其自然栖息地进行基因毒性生物监测的良好候选者。我们获得了187个外周血样本，但在13个物种中，我们只能对一个个体进行采样。观察到MNE的数量范围很广(1434至040000个红细胞)。由于每个物种的个体数量不够高，因此应谨慎考虑这一结果。猫、老鼠、长颈鹿、猪、负鼠和卷尾猴似乎是适合进行遗传毒性事件生物监测的物种。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mutation Research/Genetic Toxicology

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