Can blood group O red cells of donor origin acquire weak group A reactivity through serum A transferase of the recipient after bone marrow transplantation?
M G Wichmann, T Haferlach, M Suttorp, Y Zhang, J Neppert
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引用次数: 1
Abstract
Background: Blood group A substance was detected on red cells of a patient who received a bone marrow transplant from a blood group O donor 3.5 years ago.
Materials and methods: Peripheral blood was investigated by conventional serological techniques, fluorescence in situ hybridisation, and polymerase chain reaction.
Results: All peripheral blood cells are of donor origin. Anti-A and not anti-A, B of blood group O individuals can be absorbed to the group O red cells of the patient.
Conclusion: We suppose that the patient's residual serum A transferase attaches the appropriate sugar to substance H on the red cell membrane to form substance A.
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