H Priebe, H Dugstad, M Gacek, E Hagen, O M Homestad, A Larsen, C E Sjogren, T Thomassen
{"title":"Synthesis and characterization of iodixanol.","authors":"H Priebe, H Dugstad, M Gacek, E Hagen, O M Homestad, A Larsen, C E Sjogren, T Thomassen","doi":"10.1177/0284185195036s39903","DOIUrl":null,"url":null,"abstract":"<p><p>Iodixanol (Visipaque) is a new nonionic roentgen contrast medium intended for general use. Visipaque is a pharmaceutical formulation of iodixanol which is isotonic and iso-osmotic with blood. Two synthetic routes from 5-nitro-isophthalic acid to iodixanol are described. The chemical structure is confirmed spectroscopical data ((1)H-NMR, (13)C-NMR, FAB-MS, UV, IR and Raman). Chromotographic characteristics are related to the isomerism of iodixanol.</p>","PeriodicalId":7159,"journal":{"name":"Acta radiologica. Supplementum","volume":"399 ","pages":"21-31"},"PeriodicalIF":0.0000,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/0284185195036s39903","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta radiologica. Supplementum","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/0284185195036s39903","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
Iodixanol (Visipaque) is a new nonionic roentgen contrast medium intended for general use. Visipaque is a pharmaceutical formulation of iodixanol which is isotonic and iso-osmotic with blood. Two synthetic routes from 5-nitro-isophthalic acid to iodixanol are described. The chemical structure is confirmed spectroscopical data ((1)H-NMR, (13)C-NMR, FAB-MS, UV, IR and Raman). Chromotographic characteristics are related to the isomerism of iodixanol.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
