Serum level of IL-6 in patients with primary and secondary Sjögren's syndrome.

Abstract

The level of interleukin-6 in the serum of 17 patients suffering from the primary Sjögren's syndrome and of 16 with secondary Sjögren's syndrome were determined by means of ELISA. The mean value of IL-6 in primary and secondary Sjögren's syndrome was 2.41 pg/ml (1.45-3.37 pg/ml) and 3.01 pg/ml (1.63-4.39 pg/ml). The normal serum level of IL-6 was below 3.0 pg/ml. The serum level of IL-6 was not elevated in Sjögren's syndrome patient, there was no significant difference in the serum level of IL-6 between both groups of the patients.