[The physicochemical status of the plasma membranes of rat fatty tissue and liver in the late periods after gamma irradiation at a dose of 1 Gy. Changes in the lipid composition].

Abstract

A study was made of lipid composition of plasma membranes of adipose tissue and liver of rats at remote times (from 15 to 380 days) after single 1-Gy gamma irradiation. The changes in membrane lipids were most pronounced during the first 50 days after irradiation: the cholesterol level increased (the phospholipid content in the adipose tissue decreased) and the relative content of linoleic (18:2), arachidonic (20:4) and other unsaturated fatty acids decreased. At later times following irradiation, the molar cholesterol/phospholipid ratio in membranes of experimental animals did not vary from the control and relative content of unsaturated fatty acids somewhat increased as compared to that of intact animals of the same age.