{"title":"Oxygen radicals, a failure or a success of evolution?","authors":"G Barja","doi":"10.3109/10715769309147343","DOIUrl":null,"url":null,"abstract":"<p><p>Oxygen radicals are no doubt involved in the development of many pathological states. Nevertheless, the possibility that oxygen radical production was selected for during biological evolution in order to perform useful roles in relation to cellular metabolism is contemplated; previous data on this subject are briefly reviewed. The concept of an \"oxygen radical cycle\" is proposed as a useful theoretical model.</p>","PeriodicalId":12438,"journal":{"name":"Free radical research communications","volume":"18 2","pages":"63-70"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10715769309147343","citationCount":"52","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Free radical research communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/10715769309147343","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 52
Abstract
Oxygen radicals are no doubt involved in the development of many pathological states. Nevertheless, the possibility that oxygen radical production was selected for during biological evolution in order to perform useful roles in relation to cellular metabolism is contemplated; previous data on this subject are briefly reviewed. The concept of an "oxygen radical cycle" is proposed as a useful theoretical model.
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