Feng-Huei Lin , Haw-Chang Liu , Ming-Hsiung Hon , Cheng-Yi Wang
{"title":"Preparation and in vivo evaluation of a newly developed bioglass ceramic","authors":"Feng-Huei Lin , Haw-Chang Liu , Ming-Hsiung Hon , Cheng-Yi Wang","doi":"10.1016/0141-5425(93)90063-5","DOIUrl":null,"url":null,"abstract":"<div><p>This paper presents details of the fabrication of a glass ceramic, and its application as an artificial bone prosthetic material. This new bioglass ceramic, with composition of Na<sub>2</sub>O 8.4%, CaO 40.6%, P<sub>2</sub>O<sub>5</sub> 12% and SiO<sub>2</sub> 39%, had 160–190 MPa and 800–980 MPa of three-point bending strength and compressive strength respectively. The ceramic has a (Na, Ca) (P, Si) O<sub>3</sub> crystalline phase with a uniform crystal size of about 10μm, which was attributed to the high nucleation frequency. The rabbit condyle test showed that the material formed a tight chemical bond with biological texture and had good biocompatibility.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 6","pages":"Pages 481-486"},"PeriodicalIF":0.0000,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90063-5","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomedical engineering","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0141542593900635","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
This paper presents details of the fabrication of a glass ceramic, and its application as an artificial bone prosthetic material. This new bioglass ceramic, with composition of Na2O 8.4%, CaO 40.6%, P2O5 12% and SiO2 39%, had 160–190 MPa and 800–980 MPa of three-point bending strength and compressive strength respectively. The ceramic has a (Na, Ca) (P, Si) O3 crystalline phase with a uniform crystal size of about 10μm, which was attributed to the high nucleation frequency. The rabbit condyle test showed that the material formed a tight chemical bond with biological texture and had good biocompatibility.
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