[Adult case of aortopulmonary window with aortic regurgitation: a case report].

H Etsuda, K Mizuno, R Kato, K Arakawa, A Miyamoto, Y Nozaki, S Nakao, H Ohmura, Y Okamoto, A Uehata
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Abstract

A 45-year-old woman was admitted to our hospital because of the evaluation of heart murmur. Her height was 152 cm and body weight was 46 kg. The physical examination showed a grade 4 continuous murmur widely audible on the anterior chest wall. The chest X-ray film was normal. The electrocardiogram showed premature ventricular contractions and left ventricular (LV) hypertrophy. The two dimensional echocardiogram demonstrated the presence of moderate aortic regurgitation (AR), however, aortopulmonary window could not be detected. The aortic valve showed neither atherosclerotic nor rheumatic changes. At cardiac catheterization, pulmonary artery (PA) pressure was 20/11 mmHg and aortic pressure was 133/60 mmHg, and a step-up of O2 saturation between right ventricule and pulmonary artery (PA) was demonstrated. The aortography revealed an aortopulmonary window between the proximal ascending aorta and the main PA, and grade 2 AR. The pulmonary to systemic flow ratio averaged 1.5:1. The coronary artery and the LV wall motion was normal. Aortopulmonary window is a very rare anomaly and often requires operation in childhood because of its large left-to-right shunt in most cases. Neither an asymptomatic adult case with this anomaly nor a case with AR has not been reported so far.

成人主动脉肺窗合并主动脉反流1例。
一名45岁女性因心脏杂音被送往我院。她身高152厘米,体重46公斤。体格检查显示前胸壁有4级持续性杂音,可广泛听到。胸部x线片正常。心电图显示室性早搏及左室肥厚。二维超声心动图显示存在中度主动脉反流(AR),但未检测到主动脉肺窗。主动脉瓣未见动脉粥样硬化或风湿性病变。心导管插管时肺动脉压为20/11 mmHg,主动脉压为133/60 mmHg,右心室与肺动脉间氧饱和度升高。主动脉造影显示近端升主动脉与主动脉血动脉血之间有主动脉-肺窗,2级AR,肺流量与全身流量之比平均为1.5:1。冠状动脉及左室壁运动正常。主动脉肺窗是一种非常罕见的异常,在儿童时期通常需要手术,因为大多数情况下主动脉肺窗有很大的左向右分流。到目前为止,没有一例无症状的成人病例出现这种异常,也没有一例AR病例出现。
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