Macrophages in experimental Chagas' disease.

Abstract

The foregoing provides a basis for considering that macrophages are important in basically every aspect of the host-parasite relationship in experimental Chagas' disease. The myriad of activities of macrophages and the diverse responses of these cells to T. cruzi and various stimulatory and inhibitory cytokines as measured both in vitro and in vivo are suggestive of the complexity of the cell-cell interactions of the host during the course of infection and the evasive activities of the parasite.