{"title":"Strategies for pH gradients' optimization.","authors":"F C Celentano, E Gianazza","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A few problems arising when optimizing the composition of the mixtures to be used for IPG casting with a two chambers mixer are discussed. The behavior in the composition space of a number of objective functions is described by simulation. This allows the formalization of rules to be followed for finding the initial guess required to start the optimization algorithm and for directing and limiting the search of the objective's minimum. the results of the simulation show that a fully automatic gradient computation and optimization is possible.</p>","PeriodicalId":77007,"journal":{"name":"Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society","volume":"3 5","pages":"191-201"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A few problems arising when optimizing the composition of the mixtures to be used for IPG casting with a two chambers mixer are discussed. The behavior in the composition space of a number of objective functions is described by simulation. This allows the formalization of rules to be followed for finding the initial guess required to start the optimization algorithm and for directing and limiting the search of the objective's minimum. the results of the simulation show that a fully automatic gradient computation and optimization is possible.