Concentrations of calcium, magnesium, zinc and copper in relation to free fatty acids and cholesterol in serum of atherosclerotic men.

M Iskra, J Patelski, W Majewski
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Abstract

The concentrations of calcium, magnesium, zinc, copper, free fatty acids and total, HDL- and LDL-cholesterol in the sera of atherosclerotic men were determined. The subjects with femoral atherosclerosis were divided into two age groups: 35-59 years (N = 8, I) and 60-75 years (N = 8, II). The LDL-cholesterol concentration was increased in the elderly atherosclerotic group. Lower concentrations of calcium and magnesium, a higher concentration of copper and decreased Ca/Cu, Mg/Zn, Mg/Cu and Zn/Cu ratios were found in atherosclerosis I as compared to controls of the same age. High and positive correlations for Cu vs. total cholesterol and LDL-cholesterol (r > 0.89), but low correlation for Cu vs. HDL-cholesterol (r = 0.61) were calculated in atherosclerosis I, and negative correlations for free fatty acids vs. Ca and Mg (-r > 0.77) in atherosclerosis II.

动脉粥样硬化男性血清中钙、镁、锌和铜浓度与游离脂肪酸和胆固醇的关系。
测定动脉粥样硬化男性血清中钙、镁、锌、铜、游离脂肪酸及总胆固醇、高密度脂蛋白和低密度脂蛋白的浓度。将股骨动脉粥样硬化患者分为35-59岁(N = 8, I)和60-75岁(N = 8, II)两组,老年动脉粥样硬化组ldl -胆固醇浓度升高。与同龄对照组相比,动脉粥样硬化I型患者钙、镁浓度较低,铜浓度较高,Ca/Cu、Mg/Zn、Mg/Cu和Zn/Cu比值降低。在动脉粥样硬化I期,铜与总胆固醇和低密度脂蛋白胆固醇呈正相关(r > 0.89),但在动脉粥样硬化I期,铜与高密度脂蛋白胆固醇呈正相关(r = 0.61),在动脉粥样硬化II期,游离脂肪酸与钙和镁呈负相关(-r > 0.77)。
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