Experimental investigation of bone regeneration using Pyrost in animals.

Abstract

A study was undertaken to investigate bone regeneration in guinea pig mandibles implanted with Pyrost in comparison with artificial bone defects as controls. Bone defects were prepared in the angles of mandibles of 30 guinea pigs. The findings demonstrated that this bone substitute material stimulated bone healing, i.e. bone regeneration, in comparison with empty control cavities. Bone regeneration and new bone formation were found to be more extensive in Pyrost-implanted areas than in controls.