A red pigment synthesized by an Aspergillus parasiticus mutant as a possible new intermediate in the aflatoxin biosynthetic pathway.

M E García, M D Herce, J L Blanco, G Suárez
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引用次数: 2

Abstract

The isolation of a red pigment from an Aspergillus parasiticus mutant obtained by 366 nm u.v. light treatment of A. parasiticus NRRL 2999 is described. Studies of conversion in aflatoxin B1 and G1 suggest that the red pigment could be a possible new intermediate in the aflatoxin biosynthetic pathway not described to date, and this has been verified by studies in gas chromatography/mass spectrometry. The solubility and stability characteristics under refrigeration storage, and the influence of the temperature and the pH on its production by the A. parasiticus mutant were also studied. It grew best at 30 degrees C and pH 6. The red pigment was most soluble in ethyl acetate. The results obtained in water are emphasized where there was high stability.

寄生曲霉突变体合成的一种红色色素,可能是黄曲霉毒素生物合成途径的新中间体。
用366nm紫外光处理寄生曲霉NRRL 2999突变体,分离出一种红色色素。对黄曲霉毒素B1和G1转化的研究表明,红色色素可能是黄曲霉毒素生物合成途径中尚未描述的新中间体,这已被气相色谱/质谱研究证实。研究了冷藏条件下寄生蜂突变体的溶解度和稳定性,以及温度和pH对其产量的影响。它在30摄氏度和pH值6的条件下生长得最好。红色素最易溶于乙酸乙酯。在水中得到的结果强调有高的稳定性。
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