Synthesis and properties of N-(aminoalkyl)-4-acetyl-3,5-dimethylpyrrole-2-carboxamides hydrochlorides.

Annals of the Medical University, Bialystok, Poland = Roczniki Akademii Medycznej w Bialymstoku Pub Date : 1993-01-01

K Bielawski, J Bołtryk, D Bartulewicz, D Krajewska, A Rózański

引用次数: 0

Abstract

A series of N-(aminoalkyl)-4-acetyl-3,5-dimethylpyrrole-2-carboxamides hydrochlorides have been prepared and evaluated as cytostatic agents. General procedures were developed for constructing aminoalkyl chains on the 4-acetylpyrrole-2-carboxylic acid nuclei, utilizing 2-pyridone. The results of the preliminary biological activity have been mentioned.

本刊更多论文

N-(氨基烷基)-4-乙酰基-3,5-二甲基吡咯-2-羧酰胺类盐酸的合成与性能。

制备了一系列N-(氨基烷基)-4-乙酰基-3,5-二甲基吡咯-2-羧酰胺类盐酸药物，并对其作为细胞抑制剂进行了评价。建立了利用2-吡啶酮在4-乙酰吡咯-2-羧酸核上构建氨基烷基链的一般方法。并对其生物活性进行了初步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Annals of the Medical University, Bialystok, Poland = Roczniki Akademii Medycznej w Bialymstoku

自引率

0.00%

发文量