Budd-Chiari syndrome and Epstein-Barr virus (EBV) associated plasmacytoma in a patient with chronic active EBV infection.

S Nagafuchi, H Ishibashi, K Anzai, K Ohshima, Y Ohno, N Fukushima, M Hashizume, K Sugimachi, H Chuman, M Kikuchi
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引用次数: 2

Abstract

A 42-year-old Japanese man with chronic active Epstein-Barr virus (EBV) infection initially responded to treatment with interleukin-2 (IL-2). Six months later he developed thrombosis in the hepatic veins, and Budd-Chiari syndrome associated with severe hepatic damage was diagnosed. He also developed a solitary EBV-positive plasmacytoma in the right femur. Since these rare complications occurred after long-term IL-2 therapy, the possibility that long-term IL-2 therapy might cause Budd-Chiari syndrome and liver damage as well as EBV-associated plasmacytoma is discussed.

慢性活动性EBV感染患者的Budd-Chiari综合征和eb病毒(EBV)相关浆细胞瘤
一名患有慢性活动性eb病毒(EBV)感染的42岁日本男性最初对白细胞介素-2 (IL-2)治疗有反应。6个月后,他出现肝静脉血栓形成,并被诊断为伴有严重肝损害的Budd-Chiari综合征。他还在右侧股骨出现了一个孤立的ebv阳性浆细胞瘤。由于这些罕见的并发症发生在长期IL-2治疗后,因此我们讨论了长期IL-2治疗可能导致Budd-Chiari综合征和肝脏损害以及ebv相关浆细胞瘤的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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