Volumetric and histochemical characteristics of the glomerular zone of the rat adrenal gland 90 days after exposure to detergents.

Abstract

Using the methods of volumetry and histochemistry of the cells, we investigated the morphophysiological characteristics of the glomerular zone of the adrenal gland in rats which, after a 1-month exposure to the effects of detergents in a factory, lived through another 90 days under laboratory conditions. At the same time, control rats lived under normal conditions. The changes found in lipids and nucleic acids were manifested by different reaction of the cells in comparison with the controls. The volumetry of the cell nuclei in the glomerular zone showed statistically significant differences in the correlation of the experimental and the control animals from the aspect of the functional state of this part of the adrenal cortex. This was corroborated by the findings obtained using the methods of histochemistry.